Observational Studies in Clinical Research

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Description

Observational study designs are crucial for understanding aspects of health and disease without manipulating variables.

In this module, you will learn their strengths, limitations, and appropriate applications; explore a variety of observational study designs; and identify the kinds of bias and confounding observational studies are prone to.

By the end of this module, you will be able to:

  • Explain what observational studies should and should not be used for
  • Describe a range of observational study designs and explain their advantages and disadvantages
  • Discuss which study designs are susceptible to which kinds of bias and confounding.

Gretchen White, PhD
Assistant Professor of Medicine, Epidemiology, and Clinical and Translational Science
University of Pittsburgh 


Dr. White’s research spans the topics of alcohol use, substance use, bariatric surgery outcomes, obesity, and workforce development. She has collaborated on multiple observational studies and clinical trials. Dr. White teaches Scientific Writing and Presentation Skills, Best Practices in Clinical Research, Advanced Observational Methods, and Clinical Research Methods. She also mentors graduate, postdoctoral, and early-career investigators. 

Learn how to draft a clinical research question and proposal, identify a range of study designs for observational and experimental studies, and control for bias and confounding.

Modules in this Stack are case-based, interactive, and entirely self-paced, combining convenience and flexibility with deep, engaged learning. Take them all to earn a competency-based certificate.

Other modules in this Stack:

  • Introducing Clinical Research
  • Accounting for Bias and Confounding
  • Crafting a Clinical Research Question and Proposal
  • Observational Studies in Clinical Research